human DUSP7 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-207441
Availability:
3-5 weeks
Name:
AAV-h-DUSP7
This is an AAV expressing Human DUSP7.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DUSP7
- Gene Name
- dual specificity phosphatase 7
- Gene ID
- 1849
- Gene Synonyms
- MKPX; PYST2
- ORF Size
- 1107 bp
- RefSeq#
- BC104882
- Gene Description
- Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 (PubMed 19228121)).(supplied by OMIM, Dec 2009)
- UniGene ID
- Hs.591664
- HGNC ID
- HGNC:3073
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