human DNMT3A Over-expression AAV

Cat. No: AAV-207210

Availability: 3-5 weeks

Name: AAV-h-DNMT3A

This is an AAV expressing Human DNMT3A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DNMT3A
Gene Name: DNA methyltransferase 3 alpha
Gene ID: 1788
Gene Synonyms: DNMT3A2; M.HsaIIIA; TBRS
ORF Size: 2739 bp
RefSeq#: BC043617
Gene Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniGene ID: Hs.515840
HGNC ID: HGNC:2978