human DNAJA3 Over-expression AAV

Cat. No: AAV-207120

Availability: 3-5 weeks

Name: AAV-h-DNAJA3

This is an AAV expressing Human DNAJA3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DNAJA3
Gene Name: DnaJ heat shock protein family (Hsp40) member A3
Gene ID: 9093
Gene Synonyms: HCA57; hTID-1; TID1
ORF Size: 1443 bp
RefSeq#: BC011855
Gene Description: DNAJA3 encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.459779
HGNC ID: HGNC:11808