human DKK3 Over-expression AAV

Cat. No: AAV-207028

Availability: Immediate

Name: AAV-h-DKK3

This is an AAV expressing Human DKK3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DKK3
Gene Name: dickkopf WNT signaling pathway inhibitor 3
Gene ID: 27122
Gene Synonyms: REIC; RIG
ORF Size: 1053 bp
RefSeq#: BC007660
Gene Description: DKK3 encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
UniGene ID: Hs.292156
HGNC ID: HGNC:2893