human DIABLO Over-expression AAV

Cat. No: AAV-206982

Availability: 3-5 weeks

Name: AAV-h-DIABLO

This is an AAV expressing Human DIABLO.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DIABLO
Gene Name: diablo IAP-binding mitochondrial protein
Gene ID: 56616
Gene Synonyms: DFNA64; SMAC
ORF Size: 561 bp
RefSeq#: BC095468
Gene Description: DIABLO encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.
UniGene ID: Hs.169611
HGNC ID: HGNC:21528