human DEGS1 Over-expression AAV

Cat. No: AAV-206860

Availability: 3-5 weeks

Name: AAV-h-DEGS1

This is an AAV expressing Human DEGS1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DEGS1
Gene Name: delta 4-desaturase, sphingolipid 1
Gene ID: 8560
Gene Synonyms: DEGS; DEGS-1; Des-1; DES1; FADS7; MIG15; MLD
ORF Size: 972 bp
RefSeq#: BC000961
Gene Description: DEGS1 encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.
UniGene ID: Hs.299878
HGNC ID: HGNC:13709