human D2HGDH Over-expression AAV

Cat. No: AAV-206557

Availability: 3-5 weeks

Name: AAV-h-D2HGDH

This is an AAV expressing Human D2HGDH.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: D2HGDH
Gene Name: D-2-hydroxyglutarate dehydrogenase
Gene ID: 728294
Gene Synonyms: D2HGD
ORF Size: 1566 bp
RefSeq#: BC036604
Gene Description: D2HGDH encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
UniGene ID: Hs.535639
HGNC ID: HGNC:28358