human CYP19A1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-206448
Availability:
3-5 weeks
Name:
AAV-h-CYP19A1
This is an AAV expressing Human CYP19A1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CYP19A1
- Gene Name
- cytochrome P450 family 19 subfamily A member 1
- Gene ID
- 1588
- Gene Synonyms
- ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
- ORF Size
- 1512 bp
- RefSeq#
- BC035959
- Gene Description
- CYP19A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
- UniGene ID
- Hs.260074
- HGNC ID
- HGNC:2594
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