human CRADD Over-expression AAV

Cat. No: AAV-205957

Availability: 3-5 weeks

Name: AAV-h-CRADD

This is an AAV expressing Human CRADD.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CRADD
Gene Name: CASP2 and RIPK1 domain containing adaptor with death domain
Gene ID: 8738
Gene Synonyms: MRT34; RAIDD
ORF Size: 600 bp
RefSeq#: BC017042
Gene Description: CRADD is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
UniGene ID: Hs.591016
HGNC ID: HGNC:2340