human COX8A Over-expression AAV

Cat. No: AAV-205862

Availability: 3-5 weeks

Name: AAV-h-COX8A

This is an AAV expressing Human COX8A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: COX8A
Gene Name: cytochrome c oxidase subunit 8A
Gene ID: 1351
Gene Synonyms: COX; COX8; COX8-2; COX8L; VIII; VIII-L
ORF Size: 210 bp
RefSeq#: BC063025
Gene Description: COX8A is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
UniGene ID: Hs.433901
HGNC ID: HGNC:2294