human CNKSR2 Over-expression AAV

Cat. No: AAV-205586

Availability: 3-5 weeks

Name: AAV-h-CNKSR2

This is an AAV expressing Human CNKSR2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CNKSR2
Gene Name: connector enhancer of kinase suppressor of Ras 2
Gene ID: 22866
Gene Synonyms: CNK2; KSR2; MAGUIN
ORF Size: 3015 bp
RefSeq#: BC143839
Gene Description: CNKSR2 encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. CNKSR2 product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.555917
HGNC ID: HGNC:19701