human CHMP5 Over-expression AAV

Cat. No: AAV-205168

Availability: 3-5 weeks

Name: AAV-h-CHMP5

This is an AAV expressing Human CHMP5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CHMP5
Gene Name: charged multivesicular body protein 5
Gene ID: 51510
Gene Synonyms: C9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60
ORF Size: 660 bp
RefSeq#: BC016698
Gene Description: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.635313
HGNC ID: HGNC:26942