human CEBPB Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-204936
Availability:
3-5 weeks
Name:
AAV-h-CEBPB
This is an AAV expressing Human CEBPB.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CEBPB
- Gene Name
- CCAAT/enhancer binding protein beta
- Gene ID
- 1051
- Gene Synonyms
- C/EBP-beta; IL6DBP; NF-IL6; TCF5
- ORF Size
- 1038 bp
- RefSeq#
- BC021931
- Gene Description
- The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
- UniGene ID
- Hs.701858
- HGNC ID
- HGNC:1834
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