human CDK9 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-204866
Availability:
3-5 weeks
Name:
AAV-h-CDK9
This is an AAV expressing Human CDK9.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CDK9
- Gene Name
- cyclin dependent kinase 9
- Gene ID
- 1025
- Gene Synonyms
- C-2k; CDC2L4; CTK1; PITALRE; TAK
- ORF Size
- 1119 bp
- RefSeq#
- BC001968
- Gene Description
- CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
- UniGene ID
- Hs.706809
- HGNC ID
- HGNC:1780
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