human CDH20 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-204815
Availability:
3-5 weeks
Name:
AAV-h-CDH20
This is an AAV expressing Human CDH20.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CDH20
- Gene Name
- cadherin 20
- Gene ID
- 28316
- Gene Synonyms
- Cdh7; CDH7L3
- ORF Size
- 2406 bp
- RefSeq#
- BC101048
- Gene Description
- CDH20 is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
- UniGene ID
- Hs.671510
- HGNC ID
- HGNC:1760
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