human CAPNS1 Over-expression AAV

Cat. No: AAV-204060

Availability: 3-5 weeks

Name: AAV-h-CAPNS1

This is an AAV expressing Human CAPNS1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CAPNS1
Gene Name: calpain small subunit 1
Gene ID: 826
Gene Synonyms: CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1
ORF Size: 969 bp
RefSeq#: BC011903
Gene Description: Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
UniGene ID: Hs.515371
HGNC ID: HGNC:1481