human BTK Over-expression AAV

Cat. No: AAV-202333

Availability: 3-5 weeks

Name: AAV-h-BTK

This is an AAV expressing Human BTK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BTK
Gene Name: Bruton tyrosine kinase
Gene ID: 695
Gene Synonyms: AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
ORF Size: 1980 bp
RefSeq#: BC109080
Gene Description: BTK plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
UniGene ID: Hs.159494
HGNC ID: HGNC:1133