human BACE1 Over-expression AAV

Cat. No: AAV-201929

Availability: 3-5 weeks

Name: AAV-h-BACE1

This is an AAV expressing Human BACE1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BACE1
Gene Name: beta-secretase 1
Gene ID: 23621
Gene Synonyms: ASP2; BACE; HSPC104
ORF Size: 1506 bp
RefSeq#: BC065492
Gene Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.504003
HGNC ID: HGNC:933