human ATP6V1G3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-201776
Availability:
3-5 weeks
Name:
AAV-h-ATP6V1G3
This is an AAV expressing Human ATP6V1G3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ATP6V1G3
- Gene Name
- ATPase H+ transporting V1 subunit G3
- Gene ID
- 127124
- Gene Synonyms
- ATP6G3; Vma10
- ORF Size
- 357 bp
- RefSeq#
- BC101130
- Gene Description
- ATP6V1G3 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. ATP6V1G3 encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.127743
- HGNC ID
- HGNC:18265
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