human ATP2A2 Over-expression AAV

Cat. No: AAV-201692

Availability: 3-5 weeks

Name: AAV-h-ATP2A2

This is an AAV expressing Human ATP2A2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATP2A2
Gene Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
Gene ID: 488
Gene Synonyms: ATP2B; DAR; DD; SERCA2
ORF Size: 3129 bp
RefSeq#: BC035588
Gene Description: ATP2A2 encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniGene ID: Hs.506759
HGNC ID: HGNC:812