human APLN Over-expression AAV

Cat. No: AAV-201156

Availability: 3-5 weeks

Name: AAV-h-APLN

This is an AAV expressing Human APLN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: APLN
Gene Name: apelin
Gene ID: 8862
Gene Synonyms: APEL; XNPEP2
ORF Size: 234 bp
RefSeq#: BC021104
Gene Description: APLN encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
UniGene ID: Hs.303084
HGNC ID: HGNC:16665