human ANGPTL3 Over-expression AAV

Cat. No: AAV-200918

Availability: Immediate

Name: AAV-h-ANGPTL3

This is an AAV expressing Human ANGPTL3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ANGPTL3
Gene Name: angiopoietin like 3
Gene ID: 27329
Gene Synonyms: ANG-5; ANGPT5; ANL3; FHBL2
ORF Size: 1383 bp
RefSeq#: BC058287
Gene Description: ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
UniGene ID: Hs.209153
HGNC ID: HGNC:491