human ANAPC10 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200896
Availability:
3-5 weeks
Name:
AAV-h-ANAPC10
This is an AAV expressing Human ANAPC10.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ANAPC10
- Gene Name
- anaphase promoting complex subunit 10
- Gene ID
- 10393
- Gene Synonyms
- APC10; DOC1
- ORF Size
- 558 bp
- RefSeq#
- BC005217
- Gene Description
- ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 (PubMed 11524682)).(supplied by OMIM, Feb 2011)
- UniGene ID
- Hs.480876
- HGNC ID
- HGNC:24077
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