human AICDA Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200616
Availability:
3-5 weeks
Name:
AAV-h-AICDA
This is an AAV expressing Human AICDA.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AICDA
- Gene Name
- activation induced cytidine deaminase
- Gene ID
- 57379
- Gene Synonyms
- AID; ARP2; CDA2; HEL-S-284; HIGM2
- ORF Size
- 597 bp
- RefSeq#
- BC006296
- Gene Description
- AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
- UniGene ID
- Hs.149342
- HGNC ID
- HGNC:13203
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