human ADRBK2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200512
Availability:
3-5 weeks
Name:
AAV-h-ADRBK2
This is an AAV expressing Human GRK3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GRK3
- Gene Name
- G protein-coupled receptor kinase 3
- Gene ID
- 157
- Gene Synonyms
- ADRBK2; BARK2
- ORF Size
- 1164 bp
- RefSeq#
- BC036797
- Gene Description
- The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
- UniGene ID
- Hs.657494
- HGNC ID
- HGNC:290
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