human ACVRL1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200333
Availability:
3-5 weeks
Name:
AAV-h-ACVRL1
This is an AAV expressing Human ACVRL1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ACVRL1
- Gene Name
- activin A receptor like type 1
- Gene ID
- 94
- Gene Synonyms
- ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I
- ORF Size
- 1512 bp
- RefSeq#
- BC042637
- Gene Description
- ACVRL1 encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
- UniGene ID
- Hs.591026
- HGNC ID
- HGNC:175
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