human AARS2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200029
Availability:
3-5 weeks
Name:
AAV-h-AARS2
This is an AAV expressing Human AARS2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AARS2
- Gene Name
- alanyl-tRNA synthetase 2, mitochondrial
- Gene ID
- 57505
- Gene Synonyms
- AARSL; COXPD8; LKENP; MT-ALARS; MTALARS
- ORF Size
- 2958 bp
- RefSeq#
- BC131728
- Gene Description
- AARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
- UniGene ID
- Hs.158381
- HGNC ID
- HGNC:21022
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