AAV-Cre-GFP (AAV serotype 9) AAV

This AAV serotype 9 virus (with Capsid from AAV9 and ITR from AAV2) expresses Cre Recombinase and eGFP marker. Each gene expression is driven by its own CMV promoter.

Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.