human P53 (TP53) shRNA Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: 1854
Availability:
Immediate
Name:
Ad-h-P53 (TP53)-shRNA
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human P53 (TP53) gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in A549 cells.
The knockdown of this human gene was validated by western blot in A549 cells.
$995.00
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6 ()
- Reporter
- eGFP
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^10 PFU/ml
Gene Details
- Species
- Human
- Gene Symbol
- P53 (TP53)
- Gene ID
- 7157
- RefSeq#
- NM_000546
Product Citations
This product is referenced in the following publications:
- Waye S, etc (2015). The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. AGING.
- Kundu N, etc (2017). Use of p53-Silenced Endothelial Progenitor Cells to Treat Ischemia in Diabetic Peripheral Vascular Disease. Journal of the American Heart Association.
- H Moriyama, etc (2018). Notch signaling enhances stemness by regulating metabolic pathways through modifying p53, NF-kB, and HIF-1a. Stem Cells and Development.
Related Products
Control Products
| Product | Cat No. |
|---|---|
| Ad-GFP-U6-shRNA | 1122 |
| Ad-U6-Luc-RNAi | 1123 |
| Ad-U6-RNAi | 1640 |
| Ad-U6-shRNA-CFP | 1780 |
| Ad-U6-shRNA-mCherry | 1781 |
| Ad-U6-shRNA-RFP | 1782 |
| Ad-U6-shRNA-YFP | 1783 |
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