Cre Recombinase Adenovirus
Cat. No: 1710
Availability:
Immediate
Name:
Ad-Cre-IRES-GFP
Cre Recombinase is a Type I topoisomerase from bacteriophage P1 that catalyzes the site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals.
This adenovirus expresses both Cre recombinase and GFP. The GFP is in an IRES expression cassette.
Check out this instruction video on using our adenovirus Cre to knockout LoxP flanked gene in primary mouse embryonic fibroblasts (MEF).
$475.00
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV (ubiquitous)
- Reporter
- eGFP
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^10 PFU/ml
Gene Details
- Gene Symbol
- Cre
Product Citations
This product is referenced in the following publications:
- Zhi-Bo Wang, etc (2012). Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy. Cell Research.
- K Watanabe, etc (2013). Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice. Oncogene.
- Arntfield, ME. etc (2013). The adult mammalian pancreas contains separate precursors of pancreatic and neural crest developmental origins. Stem Cells and Development.
- Lim JA etc (2013). Loss of ß2-spectrin prevents cardiomyocyte differentiation and heart development. Cardiovascular Research.
- Anja Schrade, etc (2015). GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells. Endocrinology.
- Anja Schrade, etc (2016). GATA4 regulates blood-testis barrier function and lactate metabolism in mouse Sertoli cells. Endocrinology.
- MA Aguileta, etc (2016). A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress. Cell Death & Differentiation.
- Buo AM, etc (2016). A cost-effective method to enhance adenoviral transduction of primary murine osteoblasts and bone marrow stromal cells. Bone Research.
- Jone RA, etc (2016). RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation. JCI.
- Wang D, etc (2016). The p53-SET Interplays Reveal A New Mode of Acetylation-dependent Regulation. Nature.
- Kawamori D, etc (2017). GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in ßIRKO mice. Diabetologia.
- L Xu, etc (2018). Ablation of PPAR¿ in subcutaneous fat exacerbates age-associated obesity and metabolic decline. Aging Cell.
- O Yarychkivska, etc (2018). Independent functions of DNMT1 and USP7 at replication foci. Epigenetics & Chromatin.
- Sakamoto K, etc (2010). Janus kinase 2 is required for the initiation but not maintenance of prolactin-induced mammary cancer. Oncogene.
- G Mancino, etc (2020). The thyroid hormone inactivator enzyme, Type 3 deiodinase, is essential for coordination of keratinocyte growth and differentiation. Thyroid.
- A Darbey, etc (2020). A comparison of In Vivo Viral Targeting Systems identifies Adeno-Associated Virus Serotype 9 (AAV9) as an effective vector for Genetic Manipulation of Leydig Cells in adult mice. Andrology.
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|---|---|
| Ad-CMV-Luc | 1000 |
| Ad-GFP | 1060 |
| Ad-CMV-b-Gal | 1080 |
| Ad-Null | 1240 |
| Ad-CMV-Null | 1300 |
| Ad-RFP | 1660 |
| Ad-CFP | 1766 |
| Ad-mCherry | 1767 |
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