Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: 1504
Availability:
Immediate
Name:
Ad-iKBa
Members of the IkB family can be divided into four groups including IkB-alpha (including proteins previously referred to as pp40 and MAD-3), IkB-beta, IkB-gamma (a 70 kDa protein identical in sequence to the C-terminal domain of the p105 precursor of NFkB p50) and IkB-epsilon. Members of the IkB family exhibit differential inhibition of the DNA binding activity of various NFkB homodimeric and heterodimeric complexes. A functionally related protein, Bcl-3, is overexpressed in chronic lymphocytic leukemia.
$690.00
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV (ubiquitous)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^10 PFU/ml
Gene Details
- Species
- Human
- Gene Symbol
- iKBa
- Gene ID
- 4792
- Gene Synonyms
- IKBA, MAD-3, NFKBI, NFKBIA
- RefSeq#
- BC002601
Product Citations
This product is referenced in the following publications:
- Leychenko, A, etc (2011). Stretch-Induced Hypertrophy Activates NFkB-Mediated VEGF Secretion in Adult Cardiomyocytes. PLoS ONE.
- Thangavel C, etc (2014). The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness. Clin Cancer Res.
- NT Vu, etc (2016). Caspase-9b interacts directly with cIAP1 to drive agonist-independent activation of NF-¿B and lung tumorigenesis. Cancer Research.
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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