Akt2 (Myr) Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: 1023
Availability:
Immediate
Name:
Ad-CMV-Akt2 (Myr)
HA-Akt2 is constructed by fusing the HA tag in frame to the N termini of the coding sequence of wild type Akt2. To construct Myr-HA-Akt2, the c-Src myristoylation sequence was fused in frame to the N terminus of the HA-Akt2 (wild-type) coding sequence. Myr-HA-Akt2 is a constitutively active mutant of Akt2, and it is also referred as Akt2(ca).
$475.00
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV (ubiquitous)
- Reporter
- HA
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^10 PFU/ml
Gene Details
- Species
- Mouse
Product Citations
This product is referenced in the following publications:
- C Blackstock, etc (2014). Insulin-Like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-Binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of Col1a1 and Col1a2 mRNA. JBC.
- Kimberly A. Foster, etc (2014). Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines. Journal of Neuro-Oncology.
- M Giovarelli, etc (2014). H19 long noncoding RNA controls the mRNA decay promoting function of KSRP. PNAS.
- R Gherzi, etc (2009). Akt2-Mediated Phosphorylation Of Pitx2 Controls Ccnd1 Mrna Decay During Muscle Cell Differentiation. Cell Death & Differentiation.
- Rychahou, PG. etc (2008). Akt2 Overexpression Plays A Critical Role In The Establishment Of Colorectal Cancer Metastasis. PNAS.
- Joan Avery (2010). TRB3 Function in Cardiac Endoplasmic Reticulum Stress. Circulation Research.
- Patitucci C, etc (2017). Hepatocyte nuclear factor 1a suppresses steatosis-associated liver cancer by inhibiting PPARγ transcription. JCI.
Related Products
Control Products
| Product | Cat No. |
|---|---|
| Ad-CMV-Luc | 1000 |
| Ad-GFP | 1060 |
| Ad-CMV-b-Gal | 1080 |
| Ad-Null | 1240 |
| Ad-CMV-Null | 1300 |
| Ad-RFP | 1660 |
| Ad-CFP | 1766 |
| Ad-mCherry | 1767 |
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