human VAV3 shRNA silencing Adenovirus

Cat. No: shADV-227417

Availability: 5-8 weeks

Name: Ad-h-VAV3-shRNA

This is an Adenovirus expressing shRNA for silencing of Human VAV3.

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Species: Human
Gene Symbol: VAV3
Gene Name: vav guanine nucleotide exchange factor 3
Gene ID: 10451
ORF Size: 2541 bp
RefSeq#: NM_006113
Gene Description: VAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. VAV3 product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.267659
HGNC ID: HGNC:12659