human SAPS3 shRNA silencing Adenovirus

Product Info

Knockdown

>50% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PPP6R3

Gene Name

protein phosphatase 6 regulatory subunit 3

Gene ID

55291

Gene Synonyms

C11orf23; PP6R3; SAP190; SAPL; SAPLa; SAPS3

ORF Size

2535 bp

RefSeq#

NM_018312

Gene Description

Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 (PubMed 16769727)).(supplied by OMIM, Nov 2010)

UniGene ID

Hs.503022

HGNC ID

HGNC:1173