human UBE2M Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227024
Availability:
3-5 weeks
Name:
AAV-h-UBE2M
This is an AAV expressing Human UBE2M.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UBE2M
- Gene Name
- ubiquitin conjugating enzyme E2 M
- Gene ID
- 9040
- Gene Synonyms
- hUbc12; UBC-RS2; UBC12
- ORF Size
- 552 bp
- RefSeq#
- BC058924
- Gene Description
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
- UniGene ID
- Hs.406068
- HGNC ID
- HGNC:12491
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