human UHMK1 shRNA silencing AAV

Cat. No: shAAV-227161

Availability: 4-5 weeks

Name: AAV-h-UHMK1-shRNA

This is an AAV expressing shRNA for silencing of Human UHMK1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: UHMK1
Gene Name: U2AF homology motif kinase 1
Gene ID: 127933
Gene Synonyms: KIS; KIST; P-CIP2
ORF Size: 1035 bp
RefSeq#: NM_175866
Gene Description: The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.127310
HGNC ID: HGNC:19683