Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Nos3

Gene Name

nitric oxide synthase 3, endothelial cell

Gene ID

18127

Gene Synonyms

2310065A03Rik; ecNOS; eNOS; Nos-3

ORF Size

3609 bp

RefSeq#

BC052636

Gene Description

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets|Function: Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may downregulate eNOS activity by forming heterodimers with isoform 1.

UniGene ID

Mm.258415