human XRCC3 Over-expression AAV

Cat. No: AAV-231453

Availability: 3-5 weeks

Name: AAV-h-XRCC3

This is an AAV expressing Human XRCC3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: XRCC3
Gene Name: X-ray repair cross complementing 3
Gene ID: 7517
Gene Synonyms: CMM6
ORF Size: 1041 bp
RefSeq#: BC011725
Gene Description: XRCC3 encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. XRCC3 functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
UniGene ID: Hs.719391
HGNC ID: HGNC:12830