mouse HSD17B12 Over-expression AAV

Cat. No: AAV-261698

Availability: 3-5 weeks

Name: AAV-m-HSD17B12

This is an AAV expressing Mouse Hsd17b12.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hsd17b12
Gene Name: hydroxysteroid (17-beta) dehydrogenase 12
Gene ID: 56348
Gene Synonyms: 2610510O05Rik; AI172963; KIK-I; Kik1
ORF Size: 939 bp
RefSeq#: BC090659
Gene Description: Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
UniGene ID: Mm.22505