Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Slc24a2

Gene Name

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

Gene ID

76376

Gene Synonyms

2810021B17Rik; 6330417K15Rik; AI847460; Nckx2

ORF Size

2136 bp

RefSeq#

BC115867

Gene Description

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).

UniGene ID

Mm.127296