human SAE1 Over-expression AAV

Cat. No: AAV-222197

Availability: 3-5 weeks

Name: AAV-h-SAE1

This is an AAV expressing Human SAE1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SAE1
Gene Name: SUMO1 activating enzyme subunit 1
Gene ID: 10055
Gene Synonyms: AOS1; HSPC140; SUA1; UBLE1A
ORF Size: 1041 bp
RefSeq#: BC000344
Gene Description: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 (PubMed 9920803)).(supplied by OMIM, Mar 2010)
UniGene ID: Hs.515500
HGNC ID: HGNC:30660