rat PDGFA shRNA silencing AAV

Cat. No: shAAV-290178

Availability: 4-5 weeks

Name: AAV-r-PDGFA-shRNA

This is an AAV expressing shRNA for silencing of Rat Pdgfa.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Pdgfa
Gene Name: platelet derived growth factor subunit A
Gene ID: 25266
Gene Synonyms: PDGFACP
ORF Size: 636 bp
RefSeq#: NM_012801
Gene Description: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity).