rat SERPINB6A shRNA silencing AAV

Cat. No: shAAV-290041

Availability: 4-5 weeks

Name: AAV-r-SERPINB6A-shRNA

This is an AAV expressing shRNA for silencing of Rat Serpinb6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Serpinb6
Gene Name: serpin family B member 6
Gene ID: 291085
Gene Synonyms: Serpinb6a
ORF Size: 1140 bp
RefSeq#: NM_199085
Gene Description: SERPINB6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.