rat RAB3IP shRNA silencing AAV

Cat. No: shAAV-295102

Availability: 4-5 weeks

Name: AAV-r-RAB3IP-shRNA

This is an AAV expressing shRNA for silencing of Rat Rab3ip.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Rab3ip
Gene Name: RAB3A interacting protein
Gene ID: 29885
Gene Synonyms: RABIN3
ORF Size: 1383 bp
RefSeq#: NM_017313
Gene Description: Guanine nucleotide exchange factor for RAB8A. Mediates the release of GDP from RAB8A but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.