rat PSENEN shRNA silencing AAV

Cat. No: shAAV-294519

Availability: 4-5 weeks

Name: AAV-r-PSENEN-shRNA

This is an AAV expressing shRNA for silencing of Rat Psenen.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Psenen
Gene Name: presenilin enhancer gamma secretase subunit
Gene ID: 292788
Gene Synonyms: RGD1312037
ORF Size: 306 bp
RefSeq#: NM_001008764
Gene Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.