mouse SLC26A8 shRNA silencing AAV

Cat. No: shAAV-272261

Availability: 6-8 weeks

Name: AAV-m-SLC26A8-shRNA

This is an AAV expressing shRNA for silencing of Mouse Slc26a8.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Slc26a8
Gene Name: solute carrier family 26, member 8
Gene ID: 224661
ORF Size: 1566 bp
RefSeq#: NM_001290320
Gene Description: Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility.
UniGene ID: Mm.219530