rat PTBP1 shRNA silencing AAV

Cat. No: shAAV-290482

Availability: 4-5 weeks

Name: AAV-r-PTBP1-shRNA

This is an AAV expressing shRNA for silencing of Rat Ptbp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Ptbp1
Gene Name: polypyrimidine tract binding protein 1
Gene ID: 29497
Gene Synonyms: Ptb; PTB1; Pybp; Pybp1; Pybp2
ORF Size: 1671 bp
RefSeq#: NM_001271057
Gene Description: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.