mouse LCLAT1 shRNA silencing AAV

Cat. No: shAAV-263318

Availability: 6-8 weeks

Name: AAV-m-LCLAT1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Lclat1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Lclat1
Gene Name: lysocardiolipin acyltransferase 1
Gene ID: 225010
Gene Synonyms: Agpat8; AI181996; Alcat1; Gm91; Lycat
ORF Size: 1131 bp
RefSeq#: NM_001081071
Gene Description: Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.
UniGene ID: Mm.329194