mouse CUX1 shRNA silencing AAV

Cat. No: shAAV-256379

Availability: 6-8 weeks

Name: AAV-m-CUX1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cux1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cux1
Gene Name: cut-like homeobox 1
Gene ID: 13047
Gene Synonyms: CDP; Cutl1; Cux; Cux-1
ORF Size: 4281 bp
RefSeq#: NM_009986
Gene Description: CUX1 may be involved in intra-Golgi retrograde transport|Function: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).
UniGene ID: Mm.320317