human MAFG shRNA silencing AAV

Cat. No: shAAV-214797

Availability: 6-8 weeks

Name: AAV-h-MAFG-shRNA

This is an AAV expressing shRNA for silencing of Human MAFG.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAFG
Gene Name: MAF bZIP transcription factor G
Gene ID: 4097
Gene Synonyms: hMAF
ORF Size: 489 bp
RefSeq#: NM_002359
Gene Description: Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 (PubMed 9166829)). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).(supplied by OMIM, Mar 2010)
UniGene ID: Hs.252229
HGNC ID: HGNC:6781